Typed letter signed, one page, 8,25 x 11,5 inch, personal stationery, Munich, 6.08.1973, in German, reply letter to Mr. Temmen - concerning the use of estrogen as a prophylactic against heart attack, signed in blue ink, with intersecting letter folds - in fine to very fine condition. Accompanied by two signed photographs of Adolf Butenandt, both about 3,75 x 5,5 inch, both signed in blue ink, in very fine condition.
"[...] Ich selbst bin Chemiker und nicht Arzt und habe mich lediglich mit der Chemie und Biologie der Hormone befaßt. Dieses im voraus betont, würde ich von der Verwendung von Östrogen als Prophylaktikum gegen Herzinfarkt abraten..
Die Reaktionsunterschiede bei der Frau vor und nach der Menopause sind ja nicht nur auf die Anwesenheit oder Abwesenheit eines Hormons zurückzuführen, sondern bedingt durch eine weitgehende Änderung der ganzen endokrinen Stoffwechsellage. [...]"
"I myself am a chemist and not a doctor and have only dealt with the chemistry and biology of hormones. Having said this in advance, I would advise against using estrogen as a heart attack prophylactic.
The differences in reaction between women before and after menopause are not only due to the presence or absence of a hormone, but are also due to a major change in the entire endocrine metabolism."
Further Information on the person
(1903-1995) German biochemist, Nobel Prize for Chemistry 1939
Year of Birth: 1903
Adolf Butenandt was a German biochemist who was awarded the Nobel Prize in Chemistry in 1939 and the Grand Cross of Merit of the Federal Republic of Germany in 1965. He was born on 24th March 1903 in Bremerhaven, Germany. He studied chemistry at the University of Göttingen and graduated with a PhD in 1928.
Butenandt's research focused on the chemistry of hormones. In 1931, he isolated the female sex hormone estrone from human urine and in 1934 he isolated the male sex hormone testosterone. He was also one of the first to synthesize hormones in the laboratory. His work on hormones laid the foundation for the development of the contraceptive pill.
Butenandt also made significant contributions to the field of genetics. In 1939, he discovered the gene responsible for the development of the fruit fly. This enabled scientists to understand how genes control the development of organisms. He also discovered the structure of the genetic material DNA in 1944.
Butenandt was an important figure in the German scientific community during World War II. He was a member of the Kaiser Wilhelm Institute and was one of the few scientists who refused to cooperate with the Nazi regime. He was also active in the resistance movement and was arrested in 1942 for his involvement.
After the war, Butenandt continued his research and in 1951 he was appointed as the director of the Max Planck Institute for Biochemistry in Munich. He remained in this position until his retirement in 1971. During this time he made significant contributions to the understanding of the biochemistry of hormones and genetics.
Butenandt was a highly respected and influential scientist. He was awarded the Nobel Prize in Chemistry in 1939 and the Grand Cross of Merit of the Federal Republic of Germany in 1965. He was also a member of the German Academy of Sciences and the American Academy of Arts and Sciences. He died on 18th January 1995 in Göttingen, Germany.
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