Typed letter signed, one page, 8,25 x 11 inch, `New York University Medical Center` letterhead, New York, 26.11.1973, reply letter to Mr. Temmen in Jever - concerning hydrophobic bonds, signed in blue ballpoint ink "Severo Ochoa", with two horizontal letter folds - in nearly very fine condition.
In parts:
"In answer to your letter of November 10 I believe that the regulator (repressor) protein binds to DNA presumably through hydrogen bonds and short range forces (van der Waals and hydrophobic bonds). The affinity of the repressor for the operator gene is very high and, of course, specific. [...]"